TF family name

Cold-shock protein, DNA-binding

Desription

When Escherichia coli is exposed to a temperature drop from 37 to 10 degrees centigrade, a 4-5 hour lag phase occurs, after which growth is resumed at a reduced rate . During the lag phase, the expression of around 13 proteins, which contain specific DNA-binding regions, is increased 2-10 fold. These so-called 'cold shock' proteins are thought to help the cell to survive in temperatures lower than optimum growth temperature, by contrast with heat shock proteins, which help the cell to survive in temperatures greater than the optimum, possibly by condensation of the chromosome and organization of the prokaryotic nucleoide. A conserved domain of about 70 amino acids has been found in prokaryotic and eukaryotic DNA-binding proteins. This domain is known as the 'cold-shock domain' (CSD), part of which is highly similar to the RNP-1 RNA-binding motif.

Criteria

There is no defined InterPro Term for selection creteria.

# of TFs

1 TFs in 4 Fusarium species

References

5 reference(s) found in this TF family

Subcellular localization

PSORT2: 0 (0.00 %)
pTARGET: 0 (0.00 %)
List for Subcellular information

TF Family map

TF Family Map of Cold-shock protein, DNA-binding