Fungal Transcription Factor Database

Detalied information of TF Family

Detailed information of TF Family

TF family name

p53-like transcription factor

Desription

This domain is found in a number of transcription factors, including p53, NFATC, TonEBP, STAT-1, and NFkappaB, where it is responsible for DNA-binding. These transcription factors play diverse roles in the regulation of cellular functions. Protein interactions may also serve to stabilize the protein-DNA complex, for example in the STAT-1 dimer the SH2 (Src homology 2) domain in each monomer is coupled to the DNA-binding domain to increase stability. The DNA-binding domain consists of a beta-sandwich formed of 9 strands in 2 sheets with a Greek-key topology. This structure is found in many transcription factors, often within the DNA-binding domain.

Criteria

There is no defined InterPro Term for selection creteria.

# of TFs

22 TFs in 4 Fusarium species

References

2 reference(s) found in this TF family

Subcellular localization

PSORT2: 0 (0.00 %)
pTARGET: 0 (0.00 %)
List for Subcellular information

TF Family map

TF Family Map of p53-like transcription factor