Fungal Transcription Factor Database

Detalied information of TF Family

Detailed information of TF Family

TF family name

Winged helix repressor DNA-binding

Desription

Winged helix DNA-binding proteins share a related winged helix-turn-helix DNA-binding motif, where the 'wings', or loops, are small beta-sheets. The winged helix motif consists of two wings (W1, W2), three alpha helices (H1, H2, H3) and three beta-sheets (S1, S2, S3) arranged in the order H1-S1-H2-H3-S2-W1-S3-W2. The DNA-recognition helix makes sequence-specific DNA contacts with the major groove of DNA, while the wings make different DNA contacts, often with the minor groove or the backbone of DNA. Several winged-helix proteins display an exposed patch of hydrophobic residues thought to mediate protein-protein interactions.

Criteria

There is no defined InterPro Term for selection creteria.

# of TFs

98 TFs in 4 Fusarium species

References

2 reference(s) found in this TF family

Subcellular localization

PSORT2: 0 (0.00 %)
pTARGET: 0 (0.00 %)
List for Subcellular information

TF Family map

TF Family Map of Winged helix repressor DNA-binding