TF family name

Nucleic acid-binding, OB-fold

Desription

The OB-fold is supposed to be an oligonucleotide and oligosaccharide binding fold to study the general functional features. The OB-fold is a small beta-barrel fold formed from 5 strands connected by modulating loops. Consistently 2 or 3 loops on the same face of barrel acting as clamps to bind to their ligands. Depending on the ligand, which could be a single or double stranded DNA/RNA or an oligosaccharide, and their conformational properties the loops change in length and sequence to accommodate various ligands. Two ribosomal proteins, S17 and S1, are members of this class, and have different variations of the OB fold theme. Comparisons with other OB fold nucleic acid binding proteins suggest somewhat different mechanisms of nucleic acid recognition in each case.

Criteria

There is no defined InterPro Term for selection creteria.

# of TFs

183 TFs in 4 Fusarium species

References

0 reference(s) found in this TF family

Subcellular localization

PSORT2: 0 (0.00 %)
pTARGET: 0 (0.00 %)
List for Subcellular information

TF Family map

TF Family Map of Nucleic acid-binding, OB-fold